Azide PEG Amine, TFA Salt-北京键凯科技股份有限公司,支链聚乙二醇衍生物,直链聚乙二醇衍生物

　　键凯科技提供高品质叠氮聚乙二醇胺三氟乙酸盐，产品取代率≥95%。

　　键凯科技生产的异双功能叠氮化物PEG胺产品通常用作两种不同化学物质的交联剂或间隔物。此异功能PEG衍生物中的PEG部分可提供水溶性、生物相容性及柔性。此产品专门应用于抗体偶联药物(ADC’s)的开发。

　　键凯科技提供AZIDE-PEG-NH2TFA分子量3500 Da, 5000 Da的产品1克和10克包装。

　　键凯科技提供分装服务，需要收取分装费用，如果您需要分装为其他规格请与我们联系。

　　键凯科技同时提供其他分子量的AZIDE-PEG-NH2TFA衍生物产品，如你需要请与我司sales@jenkem.com联系。

　　键凯科技提供大批量生产产品及GMP级别产品，如需报价请与我们联系。
　　References:

　　1. Coppock, M.B., et al., A novel discovery, maturation, and assay integration approach for the development of ruggedized multi-valent capture receptors exemplified against the chikungunya virus E2 protein, Sensing and Bio-Sensing Research, 2019, V. 22.

　　2. Sun, T., et al., A targeting theranostics nanomedicine as an alternative approach for hyperthermia perfusion, Biomaterials, 2018.

　　3. Yu, S., et al., A density gradient of VAPG peptides on a cell-resisting surface achieves selective adhesion and directional migration of smooth muscle cells over fibroblasts. Acta biomaterialia, 2018, 72, pp.70-81.

　　4. Ma, H., et al., Dehydroascorbic Acid and pGPMA Dual Modified pH-Sensitive Polymeric Micelles for Target Treatment of Liver Cancer, Journal of pharmaceutical sciences, 2018, 107(2), pp.595-603.

　　5. Ma, H., DHA and pGPMA Dual Modified pH Sensitive Polymeric Micelles for Target Treatment of Liver Cancer, Journal of Pharmaceutical Sciences, 2017.

　　6. Pei, X., et al., Dehydroascorbic Acids-modified Polymer Micelles Target Cancer Cells to Enhance Anti-tumor Efficacy of Paclitaxel. Scientific Reports, 2017, 7(1):975.

　　7. Ackerman, D.S., et al., Tethered fluorogen assay to visualize membrane apposition in living cells, Bioconjugate Chemistry, 2017.

　　8. Zhou, X., et al., d‐Fructose Modification Enhanced Internalization of Mixed Micelles in Breast Cancer Cells via GLUT5 Transporters, Macromolecular Bioscience, 2017.

　　9. Guo, Y., et al., Cell Microenvironment-Controlled Antitumor Drug Releasing-Nanomicelles for GLUT1-Targeting Hepatocellular Carcinoma Therapy, ACS Applied Materials and Interfaces, 2015.

　　10.Sun, T., et al., Co-delivery of Cu(I) chelator and chemotherapeutics as a new strategy for tumor theranostic, Journal of Controlled Release, 2020, V. 321, P. 483-496.

11.Mertgen, A.S., et al., A low-fouling, self-assembled, graft co-polymer and covalent surface coating for controlled immobilization of biologically active moieties, Applied Surface Science, 2022.