Hydroxyl PEG Acetic Acid

产品代号：

HO-PEG-CM

产品纯度：

≥ 95%

包装规格：

1g, 10g, 100g等（特殊包装需收取分装费用）

分子量：

1000 Da ,2000 Da,3500 Da, 5000 Da, 7500 Da, 10000 Da,20000 Da等

如需其他分子量，请联系 sales@jenkem.com 或 010-62983737

产品咨询

产品描述

参考文献

　　键凯科技生产高质量的羟基聚乙二醇乙酸产品，产品取代率和纯度大于等于95%。

　　双端异官能团产品OH-PEG-CM，通常用作两种不同化学物质之间的交联剂或连接子。

　　具有不同官能团的聚乙二醇衍生物秉承了聚乙二醇分子的传统特性，具有良好的水溶性，生物相容性和柔性。目前双端异官能团聚乙二醇衍生物越来越多应用于抗体药物偶联物中。

　　键凯科技提供HO-PEG-CM分子量1000 Da ,2000 Da,3500 Da, 5000 Da, 7500 Da, 10000 Da,20000 Da的产品1克和10克包装。

　　键凯科技提供分装服务，需要收取分装费用，如果您需要分装为其他规格请与我们联系。

　　键凯科技同时提供其他分子量的HO-PEG-CM衍生物产品，如你需要请与我司sales@jenkem.com联系。

　　键凯科技提供大批量生产产品及GMP级别产品，如需报价请与我们联系。

　　References:

　　1. Abstiens, K., et al., Gold-tagged Polymeric Nanoparticles with Spatially Controlled Composition for Enhanced Detectability in Biological Environments, ACS Applied Nano Materials, 2019.

　　2. Abstiens, K., et al., Interaction of functionalized nanoparticles with serum proteins and its impact on colloidal stability and cargo leaching, Soft matter., 2019.

　　3. Feldmann, D.P., et al., The impact of microfluidic mixing of triblock micelleplexes on in vitro in vivo gene silencing and intracellular trafficking, Nanotechnology, 2017, 28(22):224001.

　　4. Xiao-Ding Xu, X.-D., et al., Smart and hyper-fast responsive polyprodrug nanoplatform for targeted cancer therapy, Biomaterials, 2016, 76, P. 238-249.

　　5. Jones, S.K, et al., Folate Receptor Targeted Delivery of siRNA and Paclitaxel to Ovarian Cancer Cells via Folate Conjugated Triblock Copolymer to Overcome TLR4 Driven Chemotherapy Resistance, Biomacromolecules, 2016, 17 (1), 76-87.

　　6. Cao, D., et al., Divalent Folate Modification on PEG: An Effective Strategy for Improving the Cellular Uptake and Targetability of PEGylated Polyamidoamine–Polyethylenimine Copolymer, Molecular Pharmaceutics, 2015, 12(1), 240-252.

　　7. Campbell, M.L., et al., Target-Specific Capture of Environmentally Relevant Gaseous Aldehydes and Carboxylic Acids with Functional Nanoparticles, Chem. Eur. J., 2015, 21: 14834–14842.

　　8. Wen-Wen Qi, et al., Doxorubicin-Loaded Glycyrrhetinic Acid Modified Recombinant Human Serum Albumin Nanoparticles for Targeting Liver Tumor Chemotherapy, Molecular Pharmaceutics, 2015, 12(3), 675-683.

　　9. Cong, Y., et al., Alendronate-decorated biodegradable polymeric micelles for potential bone-targeted delivery of vancomycin, Journal of Biomaterials Science, Polymer Edition, 2015, 26:11.

　　10. Wen, D., et al., LHRH-Conjugated Micelles for Targeted Delivery of Antiandrogen to Treat Advanced Prostate Cancer, Pharm Res., 2014, 31(10):2784-95.

　　11. Xiao, B., et al., Mannosylated bioreducible nanoparticle-mediated macrophage-specific TNF-α RNA interference for IBD therapy, Biomaterials, 2013, 34(30), p:7471-7482.

　　12. Ukawala, M., et al., Laminin receptor-targeted etoposide loaded polymeric micelles: a novel approach for the effective treatment of tumor metastasis, J Drug Target., 2012, 20(1):55-66.

　　13. Ukawala, M., et al., EILDV-conjugated, etoposide-loaded biodegradable polymeric micelles directing to tumor metastatic cells overexpressing α4β1 integrin, Cancer Nanotechnology, 2011, 2:1, pp 133-145.

　　14. Aryal, S., et al., PolymerCisplatin Conjugate Nanoparticles for Acid-Responsive Drug Delivery, ACS Nano, 2010, 4(1) p: 251–258.

　　15. Wei, Q., et al., Fe3O4 nanoparticles-loaded PEG–PLA polymeric vesicles as labels for ultrasensitive immunosensors. Biomaterials, 2010, 31(28): p. 7332-7339.

　　16. Lee, H., et al., The Effects of Particle Size and Molecular Targeting on the Intratumoral and Subcellular Distribution of Polymeric Nanoparticles, Molecular Pharmaceutics, 2010, 7 (4), 1195-1208.

17.Zhang, C, et al., Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy. Nature communications. 2021; 12(1):1-2.

18.Jiang, Y, et al., Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer. Nature communications. 2021, 12(1):1-4.

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Hydroxyl PEG Succinimidyl Carboxymethyl Ester

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PEG (Alkyne)2