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Methoxy PEG Succinimidyl Succinate

产品代号:

M-PEG-SS

产品纯度:

≥ 95%

包装规格:

1g, 10g, 100g等(特殊包装需收取分装费用)

分子量:

5000 Da-20000 Da,等

产品咨询:

科研客户小批量一键采购地址(小于5克)

  • 产品描述
  • 参考文献
  •   甲氧基聚乙二醇琥珀酰亚胺琥珀酸酯,在聚乙二醇键与NHS酯之间通过可降解的酯键连接,含有可降解键的线性NHS活性酯在药物缓释研发应用中应用非常广泛。

      键凯科技提供分装服务,需要收取分装费用,如果您需要分装为其他规格请与我们联系。

      键凯科技同时提供其他分子量的M-SS产品,如你需要请与我司sales@jenkem.com联系。

      键凯科技提供大批量生产产品及GMP级别产品,如需报价请与我们联系。

     

  •   References:

      1. Xiong, Q., et al., Facile fabrication of reduction-responsive supramolecular nanoassemblies for co-delivery of doxorubicin and sorafenib towards hepatoma cells, Frontiers in pharmacology, 2018, 9, p.61.

      2. Mastorakos, P., et al., Biodegradable brain-penetrating DNA nanocomplexes and their use to treat malignant brain tumors, Journal of Controlled Release, 2017, 262, P. 37-46.

      3. Mastorakos, P., et al., Biodegradable DNA Nanoparticles that Provide Widespread Gene Delivery in the Brain, Small, 2015.

      4. Jain, S., et al., Combinatorial bio-conjugation of gemcitabine and curcumin enables dual drug delivery with synergistic anticancer efficacy and reduced toxicity, RSC Adv., 2014, 4, 29193-29201.

      5. Tesfay, M.Z., et al., PEGylation of vesicular stomatitis virus extends virus persistence in blood circulation of passively immunized mice. J Virol, 2013, 87(7): p. 3752-9.

      6. Helgeson, L.A., et al, Mechanism of synergistic activation of Arp2/3 complex by cortactin and N-WASP, eLife, 2013, 2:e00884.

      7. Depp, V., et al., Native protein-initiated ATRP: A viable and potentially superior alternative to PEGylation for stabilizing biologics, Acta Biomaterialia, 5(2), 2009, p: 560-569.

           8.Narvaez-Ortiz, HY, et al., Unconcerted conformational changes in Arp2/3 complex integrate multiple activating signals to assemble functional actin networks. Current Biology. 2022.

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