8arm PEG Amine (hexaglycerol), HCl Salt

产品代号：

8ARM-PEG-NH2HCl

产品纯度：

≥ 95%

包装规格：

1g, 10g, 100g等（特殊包装需收取分装费用）

分子量：

10000Da, 20000 Da,40000 Da等

如需其他分子量，请联系 sales@jenkem.com 或 010-62983737

产品咨询

产品描述

参考文献

　　键凯科技提供高品质8ARM-NH2HCl-20K八臂聚乙二醇胺盐酸盐产品，产品取代率≥ 95%

　　键凯科技的8臂胺基产品可交联制备PEG水凝胶产品。PEG水凝胶在医疗器械和再生医学方面尤其是在药物的缓释控释，2维和3维细胞培养以及伤口的缝合和愈合方面有非常广泛的应用。键凯的8臂PEG原料来通过三聚季戊四醇和乙氧基聚合而成，每个PEG链的乙氧基单元数目不是完全相同的。键凯的多臂PEG产品的分子量指的是各臂分子量的总和。

　　键凯科技提供8ARM-NH2HCl分子量10000Da, 20000 Da,40000 Da产品 1克和10克包装。

　　键凯科技提供分装服务，需要收取分装费用，如果您需要分装为其他规格请与我们联系。

　　键凯科技同时提供其他分子量的8ARM-NH2HCl-20K产品，如你需要请与我司sales@jenkem.com联系。

　　键凯科技提供大批量生产产品及GMP级别产品，如需报价请与我们联系。

References:

Schneider, M.C., et al., An In Vitro and In Vivo Comparison of Cartilage Growth in Chondrocyte-Laden Matrix Metalloproteinase-Sensitive Poly (Ethylene Glycol) Hydrogels with Localized Transforming Growth Factor β3, Acta biomaterialia, 2019.
Armstrong, J.P., et al., Spatiotemporal quantification of acoustic cell patterning using Voronoï tessellation, Lab on a Chip, 2019.
Rao, V.V., et al., Rescuing mesenchymal stem cell regenerative properties on hydrogel substrates post serial expansion, Bioengineering & translational medicine, 2019.
Aziz, A.H., et al., The effects of dynamic compressive loading on human mesenchymal stem cell osteogenesis in the stiff layer of a bilayer hydrogel, Journal of tissue engineering and regenerative medicine, 2019.
Aziz, A.H., et al., A comparison of hMSC osteogenesis in PEG hydrogels as a function of MMP‐sensitive crosslinker and crosslink density in chemically‐defined medium, Biotechnology and Bioengineering, 2019.
Lee, J., et al., Glucose‐Responsive Trehalose Hydrogel for Insulin Stabilization and Delivery, Macromolecular bioscience, 2018, p.1700372.
Carles-Carner, M., et al., The effects of hydroxyapatite nanoparticles embedded in a MMP-sensitive photoclickable PEG hydrogel on encapsulated MC3T3-E1 pre-osteoblasts, Biomedical Materials, 2018, 13(4), p.045009.
Ovadia, E.M., et al., Designing well-defined photopolymerized synthetic matrices for three-dimensional culture and differentiation of induced pluripotent stem cells, Biomaterials science, 2018.
Li, H., et al., Preparation of photo-responsive poly(ethylene glycol) microparticles and their influence on cell viability, Journal of Colloid and Interface Science, 2018, V. 514, P. 182-189.
Tardy, B.L., et al., Formation of Polyrotaxane Particles via Template Assembly. Biomacromolecules, 2017.
Guo, C., et al., Bio-orthogonal conjugation and enzymatically triggered release of proteins within multi-layered hydrogels, Acta Biomaterialia, 2017.
Schneider, M.C., et al., Characterization of the chondrocyte secretome in photoclickable poly (ethylene glycol) hydrogels, Biotechnology and Bioengineering, 2017.
Aziz, A.H., et al., Mechanical characterization of sequentially layered photo-clickable thiol-ene hydrogels, Journal of the Mechanical Behavior of Biomedical Materials, 2017, V. 65, p. 454-465.
Braunger, J.A., et al., Interactions between circulating nanoengineered polymer particles and extracellular matrix components in vitro. Biomaterials Science, 2017.
Liu, Y., et al., Trehalose Glycopolymer Enhances Both Solution Stability and Pharmacokinetics of a Therapeutic Protein, Bioconjugate Chemistry, 2017.
Shih, H., Improving gelation efficiency and cytocompatibility of visible light polymerized thiol-norbornene hydrogels via addition of soluble tyrosine, Biomaterials Science, 2017, 5(3), 589-99.
Chu, S., et al., Understanding the Spatiotemporal Degradation Behavior of Aggrecanase-Sensitive Poly (ethylene glycol) Hydrogels for use in Cartilage Tissue Engineering, Tissue Engineering, 2017.
Shin, D.S., et al., Synthesis of microgel sensors for spatial and temporal monitoring of protease activity, ACS Biomaterials Science & Engineering, 2017.
Jeon, O., et al., Dual-crosslinked hydrogel microwell system for formation and culture of multicellular human adipose tissue-derived stem cell spheroids. Journal of Materials Chemistry B, 2016, 4(20), 3526-33.
Ma, Z., et al., Folate‐Conjugated Polylactic Acid–Silica Hybrid Nanoparticles as Degradable Carriers for Targeted Drug Delivery, On‐Demand Release and Simultaneous Self‐Clearance, ChemPlusChem, 2016.
Maisonneuve, B. G. C., et al., Effects of Synthetic Biomacromolecule Addition on the Flow Behavior of Concentrated Mesenchymal Cell Suspensions, Biomacromolecules, 2015, 16(1), 275-283.
Hennig, R., et al., Branched Polymer–Drug Conjugates for Multivalent Blockade of Angiotensin II Receptors, Molecular Pharmaceutics, 2015, 12 (9), 3292-3302.
Skaalure, S.C., et al., An Enzyme-Sensitive PEG Hydrogel Based on Aggrecan Catabolism for Cartilage Tissue Engineering. Advanced Healthcare Materials, 2015, 4, 420–431.
Sarfare, S., et al., Biocompatibility of a Synthetic Biopolymer for the Treatment of Rhegmatogenous
Retinal Detachment, J Clin Exp Ophthalmol, 2015, 6, 475.
Frith, J.E., et al., Effects of bound versus soluble pentosan polysulphate in PEG/HA-based hydrogels tailored for intervertebral disc regeneration. Biomaterials, 2014, 35(4), p. 1150-1162.
Jeon, O., et al., Single and dual crosslinked oxidized methacrylated alginate/PEG hydrogels for bioadhesive applications. Acta Biomaterialia, 2014, 10(1), p. 47-55.
McKinnon, D.D., et al., Design and Characterization of a Synthetically Accessible, Photodegradable Hydrogel for User-Directed Formation of Neural Networks, Biomacromolecules, 2014, 15, 2808−2816.
Amoozgar, Z., et al., Dual-layer surface coating of PLGA-based nanoparticles provides slow-release drug delivery to achieve metronomic therapy in a paclitaxel-resistant murine ovarian cancer model, Biomacromolecules, 2014, 15(11), 4187-94.
Chung, J., et al., Modular Multi-enzyme Cascade Process Using Highly Stabilized Enzyme Microbeads, Green Chem., 2014, 16, 1163-1167.
McKinnon, D.D., Process Extension from Embryonic Stem Cell-Derived Motor Neurons through Synthetic Extracellular Matrix Mimics, Univ of Colorado at Boulder, 2014, 3635878.
Cui, J., et al., Super-Soft Hydrogel Particles with Tunable Elasticity in a Microfluidic Blood Capillary Model, Advanced Materials, 2014, 26(43), 7295-7299.
Gandavarapu, N. R., et al., Osteogenic differentiation of human mesenchymal stem cells on α5 integrin binding peptide hydrogels is dependent on substrate elasticity, Biomaterials Science, 2014, 2(3), 352-361.
McKinnon, D.D., et al., Measuring cellular forces using bis-aliphatic hydrazone crosslinked stress-relaxing hydrogels, Soft Matter, 2014, 10, 9230.
Strehin, I., et al., Hydrogels Formed by Oxo-ester Mediated Native Chemical Ligation, Biomater Sci., 2013, 1(6), 603–613.
Barrett, D. G., et al., pH-Based Regulation of Hydrogel Mechanical Properties Through Mussel-Inspired Chemistry and Processing, Adv Funct Mater, 2013, 23(9), 1111-1119.
Chung, J., et al., Magnetic-separable robust microbeads using a branched polymer for stable enzyme immobilization, Reactive and Functional Polymers, 2013, 73:1, P. 39-45.
Jeon, O., et al., Regulation of Stem Cell Fate in a Three‐Dimensional Micropatterned Dual‐Crosslinked Hydrogel System, Advanced functional materials, 2013, 23.38, 4765-4775.
Giorgi, M.E., et al., Improved bioavailability of inhibitors of Trypanosoma cruzi trans-sialidase: PEGylation of lactose analogs with multiarm polyethyleneglycol, Glycobiology, 2012, 22(10), p. 1363-1373.
Zhou, J., et al., Real-time detection of implant-associated neutrophil responses using a formyl peptide receptor-targeting NIR nanoprobe, International Journal of Nanomedicine, 2012, 7 2057–2068.
Christman, K.L., et al., Surface Patterning for Generating Defined Nanoscale Matrices, Stem Cells for Myocardial Regeneration, 2010, v. 660, p. 255-263.
Tan, H., et al., Novel Multi-arm PEG-based Hydrogels for Tissue Engineering, Journal of biomedical materials research Part A., 2010, 92(3), 979-987.
Schroeder, M. E., et al., Collagen networks within 3D PEG hydrogels support valvular interstitial cell matrix mineralization, Acta Biomaterialia, 2021, V. 119, P. 197-210.
Schoonraad, SA, et al., The Effects of Stably Tethered BMP-2 on MC3T3-E1 Preosteoblasts Encapsulated in a PEG Hydrogel. Biomacromolecules. 2021, 22(3):1065-79.
Caldwell, AS, et al, Mesenchymal stem cell‐inspired microgel scaffolds to control macrophage polarization. Bioengineering & Translational Medicine. 2021, 6(2):e10217.
Song, J, et al, Influence of Poly (ethylene glycol) Molecular Architecture on Particle Assembly and Ex Vivo Particle–Immune Cell Interactions in Human Blood. ACS nano. 2021.
Batan, D, et al., Hydrogel cultures reveal Transient Receptor Potential Vanilloid 4 regulation of myofibroblast activation and proliferation in valvular interstitial cells. The FASEB Journal. 2022.
Yu, Y, et al., A 3D printed mimetic composite for the treatment of growth plate injuries in a rabbit model. NPJ Regenerative Medicine. 2022;7(1):1-4.
Schroeder, M. E., et al., Osteopontin activity modulates sex‐specific calcification in engineered valve tissue mimics, Bioengineering & translational medicine 2023, 8.1, e10358.