4arm PEG Maleimide (pentaerythritol)

产品代号：

4ARM-PEG-MAL

产品纯度：

≥ 90%

包装规格：

1g, 10g, 100g等（特殊包装需收取分装费用）

分子量：

10000Da, 20000 Da,40000 Da等

如需其他分子量，请联系 sales@jenkem.com 或 010-62983737

产品咨询

产品描述

参考文献

　　键凯科技提供高品质四臂聚乙二醇马来酰亚胺产品，产品取代率>90%。

　　键凯科技的4臂马来酰亚胺产品可用来交联制备PEG水凝胶产品。PEG水凝胶在医疗器械和再生医学方面尤其是在药物的缓释控释，2维和3维细胞培养以及伤口的缝合和愈合方面有非常广泛的应用。键凯的4臂PEG原料来源于季戊四醇和环氧乙烷聚合而成，每个PEG链的乙氧基单元数目不是完全相同的。键凯的多臂PEG产品的分子量指的是各臂分子量的总和。

　　键凯科技提供4ARM-MAL-20K分子量10000Da, 20000 Da,40000 Da产品 1克和10克包装。

　　键凯科技提供分装服务，需要收取分装费用，如果您需要分装为其他规格请与我们联系。

　　键凯科技同时提供其他分子量的4ARM-MAL产品，如你需要请与我司sales@jenkem.com联系。

　　键凯科技提供大批量生产产品及GMP级别产品，如需报价请与我们联系。

References:

Li, H., et al., Synthesis of thiol-terminated PEG-functionalized POSS cross-linkers and fabrication of high-strength and hydrolytic degradable hybrid hydrogels in aqueous phase, European Polymer Journal, 2019, 116:74-83.
Atallah, P., et al., Charge-tuning of glycosaminoglycan-based hydrogels to program cytokine sequestration, Faraday Discussions, 2019.
Dai, J., et al., Modifying decellularized aortic valve scaffolds with stromal cell-derived factor-1α loaded proteolytically degradable hydrogel for recellularization and remodeling, Acta biomaterialia, 2019.
Tunn, I., et al., Bioinspired Histidine–Zn2+ Coordination for Tuning the Mechanical Properties of Self-Healing Coiled Coil Cross-Linked Hydrogels, Biomimetics, 2019, 4(1):25.
Jansen, L.E., et al., Control of thiol-maleimide reaction kinetics in PEG hydrogel networks, Acta Biomaterialia, 2018, V. 70, P. 120-128.
Schweikle, M., et al.,. Injectable synthetic hydrogel for bone regeneration: Physicochemical characterisation of a high and a low pH gelling system, Materials Science and Engineering: C, 2018, 90, pp.67-76.
Brooks, E.A., et al., Complementary, Semi-automated Methods for Creating Multi-dimensional, PEG-based Biomaterials, ACS Biomaterials Science & Engineering, 2018.
Matsumura, K., et al., Urokinase injection-triggered clearance enhancement of a 4-arm PEG-conjugated 64 Cu-bombesin analog tetramer: A novel approach for the improvement of PET imaging contrast, International journal of pharmaceutics, 2018.
Yang, T., et al., Superparamagnetic colloidal chains prepared via Michael-addition, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2018, V. 540, P. 23-28.
Shen, J., et al., Hydrolytically degradable POSS-PEG hybrid hydrogels prepared in aqueous phase with tunable mechanical properties, swelling ratio and degradation rate, Reactive and Functional Polymers, 2018, V. 123, P. 91-96.
Day, J.R., et al., The impact of functional groups of poly(ethylene glycol) macromers on the physical properties of photo-polymerized hydrogels and the local inflammatory response in the host, Acta Biomaterialia, 2018, Vol. 67, P. 42-52.
Tondera, C., et al., In Vivo Examination of an Injectable Hydrogel System Crosslinked by Peptide–Oligosaccharide Interaction in Immunocompetent Nude Mice, Advanced Functional Materials, 2017, 27(15).
Maitz, M.F., et al., Adaptive release of heparin from anticoagulant hydrogels triggered by different blood coagulation factors, Biomaterials, 2017, 135:53-61.
Robinson, K.G., et al., Reduced Arterial Elasticity due to Surgical Skeletonization is Ameliorated by Abluminal PEG Hydrogel, Bioengineering & Translational Medicine, 2017.
Bas, O., et al., Biofabricated soft network composites for cartilage tissue engineering. Biofabrication, 2017.
Nowak, M., et al., Modular GAG-matrices to promote mammary epithelial morphogenesis in vitro, Biomaterials 2017, 112, p. 20-30.
Hesse, E., et al., Peptide‐functionalized starPEG/heparin Hydrogels Direct Mitogenicity, Cell Morphology and Cartilage Matrix Distribution in vitro and in vivo. Journal of Tissue Engineering and Regenerative Medicine, 2017.
Gencoglu, M.F., et al., Comparative study of multicellular tumor spheroid formation methods and implications for drug screening. ACS Biomaterials Science & Engineering, 2017.
Skoumal, M.J, Localized Tolerance and Development of an Alternative Transplant Site to Treat Type 1 Diabetes, University of Michigan, 2017.
Wu, F., et al., A novel synthetic microfiber with controllable size for cell encapsulation and culture. Journal of Materials Chemistry B, 2016, 4(14):2455-65.
Taubenberger, A.V., et al., 3D extracellular matrix interactions modulate tumour cell growth, invasion and angiogenesis in engineered tumour microenvironments, Acta biomaterialia, 2016.
Darling, N.J., et al., Controlling the kinetics of thiol-maleimide Michael-type addition gelation kinetics for the generation of homogenous poly (ethylene glycol) hydrogels, Biomaterials, 2016.
Danmark, S., et al., Tailoring Supramolecular Peptide-Poly (ethylene glycol) Hydrogels by Coiled Coil Self-Assembly and Self-Sorting. Biomacromolecules, 2016.
Rios, P.D., et al., Mold‐casted non‐degradable, islet macro‐encapsulating hydrogel devices for restoration of normoglycemia in diabetic mice. Biotechnology and bioengineering, 2016.
Wang, J.J, et al., Biomimetic synthesis of platelet-shaped hydroxyapatite mesocrystals in a collagen mimetic peptide–PEG hybrid hydrogel, Materials Letters, 2015, 159, P. 150-153.
Mahadevaiah, S., et al., Decreasing matrix modulus of PEG hydrogels induces a vascular phenotype in human cord blood stem cells, Biomaterials, 2015, 62, p. 24-34.
Griffin, D. R., et al., Hybrid Photopatterned Enzymatic Reaction (HyPER) for In situ Cell Manipulation, Chembiochem : a European journal of chemical biology, 2014, 15(2): 233-242.
Liang, Y., et al., Multifunctional lipid-coated polymer nanogels crosslinked by photo-triggered Michael-type addition, Polym. Chem., 2014, 5, 1728-1736.
Maitz, M.F., et al., Bio-responsive polymer hydrogels homeostatically regulate blood coagulation, Nat Commun, 2013, 4.
Robinson, K. G., et al., Differential effects of substrate modulus on human vascular endothelial, smooth muscle, and fibroblastic cells, Journal of Biomedical Materials Research, 2012, 100(5): 1356-1367.
Lu, H.D., et al., Injectable shear-thinning hydrogels engineered with a self-assembling Dock-and-Lock mechanism, Biomaterials, 2012, 33(7): p. 2145-2153.
Soon, A.S.C., et al., Modulation of fibrin matrix properties via knob:hole affinity interactions using peptide–PEG conjugates, Biomaterials, 2011, 32:19, P. 4406-4414.
Nie, T., et al., Production of heparin-containing hydrogels for modulating cell responses, Acta Biomaterialia, 2009, 5(3), p: 865-875.
Schirmer, L., et al., Glycosaminoglycan-based hydrogels with programmable host reactions, Biomaterials, 2020, V. 228.
Wang, J., et al., An injectable PEG hydrogel controlling neurotrophin-3 release by affinity peptides,Journal of Controlled Release, 2021, 330, P. 575-586.
Scott, R. A., et al., Substrate stiffness directs the phenotype and polarization state of cord blood derived macrophages, Acta Biomaterialia, 2021, V. 122, P. 220-235.
Cheng, L., et al., Bioresponsive micro-to-nano albumin-based systems for targeted drug delivery against complex fungal infections. Acta Pharmaceutica Sinica B. 2021
Liu, S, et al., Injectable and Degradable PEG Hydrogel with Antibacterial Performance for Promoting Wound Healing. ACS Applied Bio Materials. 2021, 4(3):2769-80.
Guo, R, et al., Anticalcification Potential of POSS-PEG Hybrid Hydrogel as a Scaffold Material for the Development of Synthetic Heart Valve Leaflets. ACS Applied Bio Materials. 2021, 4(3):2534-43.
Kim, J, et al., In Situ Crosslinked Hydrogel Depot for Sustained Antibody Release Improves Immune Checkpoint Blockade Cancer Immunotherapy. Nanomaterials. 2021, 11(2):471.
Xu, Y., et al., A self-assembled dynamic extracellular matrix-like hydrogel system with multi-scale structures for cell bioengineering applications, Acta Biomaterialia, V. 162, 2023, P. 211-225.
Martin, K. E., et al., Hydrolytic hydrogels tune mesenchymal stem cell persistence and immunomodulation for enhanced diabetic cutaneous wound healing, Biomaterials, 301, 2023.
Ilochonwu, B. C., et al., Thermo-responsive Diels-Alder stabilized hydrogels for ocular drug delivery of a corticosteroid and an anti-VEGF fab fragment, Journal of Controlled Release, 361, 2023.