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OPSS PEG Succinimidyl Carboxymethyl Ester

产品代号:

OPSS-PEG-SCM

产品纯度:

≥ 90%

包装规格:

1g, 10g, 100g等(特殊包装需收取分装费用)

分子量:

2000 Da,3500 Da, 5000 Da, 7500 Da等

产品咨询:

科研客户小批量一键采购地址(小于5克)

  • 产品描述
  • 参考文献
  •   键凯科技提供高品质邻二硫吡啶聚乙二醇琥珀酰亚胺羧甲基酯,产品取代率>90%。

      键凯科技生产的异双功能巯基吡啶PEG琥珀酰亚胺基羧甲基酯产品通常用作两种不同化学物质的交联剂或间隔物。此异功能PEG衍生物中的PEG部分可提供水溶性、生物相容性及柔性。此产品专门应用于抗体偶联药物(ADC’s)的开发。

      键凯科技提供OPSS-PEG-SCM产品的常规分子量是2000 Da,3500 Da, 5000 Da, 7500 Da的多种规格包装产品。

      键凯科技同时提供其他分子量的OPSS-PEG-SCM衍生物产品,如你需要请与我司sales@jenkem.com联系。

           键凯科技提供分装服务,需要收取分装费用,如果您需要分装为其他规格请与我们联系。

         键凯科技提供大批量生产产品及GMP级别产品,如需报价请与我们联系。

  •   References:

      1. Ye, J., et al., Cellular uptake mechanism and comparative in vitro cytotoxicity studies of monomeric LMWP-siRNA conjugate, Journal of Industrial and Engineering Chemistry, 2018.

      2. Lee, K., et al., Enhanced accumulation of theranostic nanoparticles in brain tumor by external magnetic field mediated in situ clustering of magnetic nanoparticles, Journal of Industrial and Engineering Chemistry, 2017.

      3. Feng, Y., et al., Evaluation of Electrospun PCL-PIBMD Meshes Modified with Plasmid Complexes in Vitro and in Vivo. Polymers, 2016, 8(3), p.58.

      4. Braun, G.B., et al., Urokinase-controlled tumor penetrating peptide. Journal of Controlled Release, 2016, 232:188-95.

      5. Shin M.C., et al., Preparation and Characterization of Gelonin-Melittin Fusion Biotoxin for Synergistically Enhanced Anti-Tumor Activity. Pharmaceutical research, 2016, 1-1.

      6. Zhou, F., et al., Targeted delivery of microRNA-126 to vascular endothelial cells via REDV peptide modified PEG-trimethyl chitosan. Biomaterials science, 2016, 4(5):849-56.

      7. Sugahara, K.N., et al., Tumor-Penetrating iRGD Peptide Inhibits Metastasis, Mol. Cancer Ther., 2015, 14, 120.

      8. Wang, H., et al., Targeting REDV peptide functionalized polycationic gene carrier for enhancing the transfection and migration capability of human endothelial cells, J. Mater. Chem. B, 2015, 3, 3379-3391.

      9. Braun, G.B., Etchable and Bright Silver Nanoparticle Probes for Cell Internalization Assays, Nature Materials, 2014, 13, p: 904–911.

      10. Pang, H.B., et al., An endocytosis pathway initiated through ​neuropilin-1 and regulated by nutrient availability, Nature Communications, 2014, 5:4904.

      11. Shin, M.C., et al., Combination of antibody targeting and PTD-mediated intracellular toxin delivery for colorectal cancer therapy, Journal of Controlled Release, 194(28), 2014, p: 197-210.

      12. Minai, L., et al., High levels of reactive oxygen species in gold nanoparticle-targeted cancer cells following femtosecond pulse irradiation, Scientific Reports, 2013, 3 : 2146.

      13. Yeheskely-Hayon, D., et al., Optically Induced Cell Fusion Using Bispecific Nanoparticles, Small, 2013.

      14. Agemy, L., et al., Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma PNAS, 2011, 108(42), 17450-17455.

      15. Whaley Bishnoi, S., et al., SERS Biodetection Using Gold–Silica Nanoshells and Nitrocellulose Membranes, Analytical Chemistry, 2011, 83(11), p: 4053–4060.

           16.Laskar, P, et al., Octadecyl chain-bearing PEGylated poly (propyleneimine)-based dendrimersomes: physicochemical studies, redox-responsiveness, DNA condensation, cytotoxicity and gene delivery to cancer cells. Biomaterials Science. 2021, 9(4):1431-48.

           17.Tobi, A, et al., Silver nanocarriers targeted with a CendR peptide potentiate the cytotoxic activity of an anticancer drug. Advanced Therapeutics. 2021, 4(1):2000097.

           18.Pleiko, K, et al., In vivo phage display: identification of organ-specific peptides using deep sequencing and differential profiling across tissues. Nucleic acids research. 2021, 49(7):e38.

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