Methoxy PEG Succinimidyl Succinate

　　甲氧基琥珀酸琥珀酰亚胺酯，在聚乙二醇键与NHS酯之间通过可降解的酯键连接，含有可降解键的线性NHS活性酯在药物缓释研发应用中应用非常广泛。

　　键凯科技提供M-SS分子量的5000 Da，20000Da的产品1克和10克包装。

　　键凯科技提供分装服务，需要收取分装费用，如果您需要分装为其他规格请与我们联系。

　　键凯科技同时提供其他分子量的M-SS产品，如你需要请与我司sales@jenkem.com联系。

　　键凯科技提供大批量生产产品及GMP级别产品，如需报价请与我们联系。

References:

1. Xiong, Q., et al., Facile fabrication of reduction-responsive supramolecular nanoassemblies for co-delivery of doxorubicin and sorafenib towards hepatoma cells, Frontiers in pharmacology, 2018, 9, p.61.

2. Mastorakos, P., et al., Biodegradable brain-penetrating DNA nanocomplexes and their use to treat malignant brain tumors, Journal of Controlled Release, 2017, 262, P. 37-46.

3. Mastorakos, P., et al., Biodegradable DNA Nanoparticles that Provide Widespread Gene Delivery in the Brain, Small, 2015.

4. Jain, S., et al., Combinatorial bio-conjugation of gemcitabine and curcumin enables dual drug delivery with synergistic anticancer efficacy and reduced toxicity, RSC Adv., 2014, 4, 29193-29201.

5. Tesfay, M.Z., et al., PEGylation of vesicular stomatitis virus extends virus persistence in blood circulation of passively immunized mice. J Virol, 2013, 87(7): p. 3752-9.

6. Helgeson, L.A., et al, Mechanism of synergistic activation of Arp2/3 complex by cortactin and N-WASP, eLife, 2013, 2:e00884.

7. Depp, V., et al., Native protein-initiated ATRP: A viable and potentially superior alternative to PEGylation for stabilizing biologics, Acta Biomaterialia, 5(2), 2009, p: 560-569.